This course surveys the impact of human factors on crewed missions, challenges of continuous operational support for long-duration spaceflight, and approaches for analysis and interpretation of human factors data. Students will assess the participation of humans in space exploration and the abilities to perform physically and psychologically for extended periods in harsh environments, with unique gravitation and radiation characteristics. Human factors and human performance issues in general applications will be explored, topics may include: cognitive engineering and human- centered design principles applicable to life-critical systems, addressing human-centered automation, human workload, cognitive modeling, situational awareness, risk taking and applied user experience design and evaluation.